Heat Shock Protein 70b’ (hsp70b’) Expression and Release in Response to Human Oxidized Ldl Immune Complexes in Macrophages
نویسندگان
چکیده
HUMAN OXIDIZED LDL IMMUNE COMPLEXES IN MACROPHAGES Kent J. Smith, Waleed O Twal, Farzan Soodavar, Gabriel Virella, Maria F Lopes-Virella, and Samar M Hammad From Department of Regenerative Medicine and Cell Biology, Microbiology and Immunology, and the Division of Endocrinology, Department of Medicine, Medical University of South Carolina, Charleston, SC 29425, and the Department of Veteran Affairs, Ralph H. Johnson Veterans Affairs Medical Center, Charleston, SC 29401 Running head: HSP70B’ induction by oxidized LDL immune complexes Address correspondence to: Samar M. Hammad, Department of Regenerative Medicine and Cell Biology, Medical University of South Carolina, 114 Doughty Street, 630B, P.O. Box 250776, Charleston, SC, 29425. Tel.: (843) 876-5200; Fax: (843) 792-0664; E-Mail: [email protected]
منابع مشابه
Differential Trafficking of Oxidized LDL and Oxidized LDL Immune Complexes in Macrophages: Impact on Oxidative Stress
BACKGROUND Oxidized low-density lipoproteins (oxLDL) and oxLDL-containing immune complexes (oxLDL-IC) contribute to formation of lipid-laden macrophages (foam cells). It has been shown that oxLDL-IC are considerably more efficient than oxLDL in induction of foam cell formation, inflammatory cytokines secretion, and cell survival promotion. Whereas oxLDL is taken up by several scavenger receptor...
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